Lab News

@ryanhpurcell of the Bassell Lab publishes collaborative paper in Science Advances
The Bassell Lab and Mulle Lab published, “Cross-species analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion,” by Ryan Purcell and Esra Sefik et. al  

*This publication is also highlighted in Neuroscience News, ScienceDailyNews Medical, GEN, EurekAlert, and in the Emory News Center.

The Bassell and Huber lab publishes paper in Neurobiology of Disease.
The Bassell and Huber lab published, “FMRP phosphorylation and interactions with Cdh1 regulate association with dendritic RNA granules and MEF2-triggered synapse elimination,” in Neurobiology of Disease.

@BassellLab and @EricTWang Publish Collaborative Nature Communications Paper Supported by MPI NIH R01 grant
The Bassell Lab and Wang Lab published, "Muscleblind-like proteins use modular domains to localize RNAs by riding kinesins and docking to membranes," by Ryan P. Hildebrandt and Kathryn R. Moss et al.

 

 

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In MEMORY OF KUN LIN

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With a heavy heart we communicate the recent tragic passing of my graduate student, our colleague and friend, Kun Lin, on February 12, 2021. Our tears and sadness are hard. Kun was full of radiant energy, intellect and passion, kind and generous, with dreams to become a professor. To learn more about Kun's short but wonderful life, to share your thoughts and contributions:

GOFUNDME - To provide support to Kun's parents for medical, funeral, and other costs, please visit.

KUDOBOARD - to share your thoughts and photos about Kun.

KUN LIN MEMORIAL SCHOLARSHIP FUND

MEMORIAL BENCH - To contribute to the Kun Lin Memorial Bench, please donate to the Atlanta Botanical Garden (Kun’s favorite place in Atlanta, GA). Please indicate donations are “In memory of Kun Lin”.

THE KUN LIN MEMORIAL LECTURE:

We are grateful for the kind and generous donations from faculty, students and friends to establish the Kun Lin Memorial lecture. The lecture topics will relate to Kun's research interests in cellular and brain imaging, and RNA and synapse biology in health and disease.

-Gary J. Bassell, PhD, Professor and Chair

Highlights

Gary Bassell and Eric Wang Receive NINDS Funding for Collaborative Research on Myotonic Dystrophy

Drs. Bassell and Wang The National Institute of Neurological Disorders and Stroke has awarded Bassell’s and Wang’s laboratories $2.2 million over five years to examine the neuronal function of Muscleblind-like proteins, which play key roles in myotonic dystrophy.

Read full story in Emory Health Sciences Blog.

LISTEN to a joint talk recently presented by Gary Bassell and Eric Wang at the RNA Society annual meeting in May 2020.

Recent Publications

Hildebrandt RP, Moss KR, Janusz-Kaminska A, Knudson LA, Denes LT, Saxena T, Boggupalli DP, Li Z, Lin K, Bassell GJ, Wang ET. Muscleblind-like proteins use modular domains to localize RNAs by riding kinesins and docking to membranes. Nat Commun. 2023;14(1):3427. Published 2023 Jun 9. doi:10.1038/s41467-023-38923-6.

Ifrim MF, Janusz-Kaminska A, Bassell GJ. Development of single-molecule ubiquitination mediated fluorescence complementation to visualize protein ubiquitination dynamics in dendrites. Cell Rep. 2022 Nov 15;41(7):111658. doi: 10.1016/j.celrep.2022.111658. PMID: 36384114.

Edokpolor KS, Banerjee A, McEachin ZT, Gu J, Kosti A, Arboleda JD, García PS, Wang ET, Bassell GJ. Altered Behavioral Responses Show GABA Sensitivity in Muscleblind-Like 2-Deficient Mice: Implications for CNS Symptoms in Myotonic Dystrophy. eNeuro. 2022 Oct 10;9(5):ENEURO.0218-22.2022. doi: 10.1523/ENEURO.0218-22.2022. PMID: 36150891; PMCID: PMC9557336.
*This publication is also reported by the Emory News Center.

Kang Y, Zhou Y, Li Y, Han Y, Xu J, Niu W, Li Z, Liu S, Feng H, Huang W, Duan R, Xu T, Raj N, Zhang F, Dou J, Xu C, Wu H, Bassell GJ, Warren ST, Allen EG, Jin P, Wen Z. A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies. Nat Neurosci. 2021 Oct;24(10):1377-1391. doi: 10.1038/s41593-021-00913-6. Epub 2021 Aug 19. PMID: 34413513; PMCID: PMC8484073.

Pant DC, Parameswaran J, Rao L, Loss I, Chilukuri G, Parlato R, Shi L, Glass JD, Bassell GJ, Koch P, Yilmaz R, Weishaupt JH, Gennerich A, Jiang J. ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain-of-function. EMBO Rep. 2022 Aug 3;23(8):e54234. doi: 10.15252/embr.202154234. Epub 2022 Jun 23. PMID: 35735139; PMCID: PMC9346498.

 


HOnors, awards, and fellowships 

2023      Gary Bassell receives NIH R21 Exploratory/Developmental Research Grant Award (R21NS133933)

2023      Adam Kosti receives NIH F32 Ruth L. Kirschstein Postdoctoral Individual National Research Service Award (F32MH135636)

2023      Ryan Purcell receives NIH K01 - Research Scientist Development Award (K01MH133970) 

2023      Ryan Purcell, Gary Bassell, & Erica Duncan receives a Georgia CTSA i3 VA pilot grant (Round #136 SOM I3/Atlanta VA Research)

2023      Maxine Robinette & Nisha Raj receives a NICHD Diversity Supplement awarded to the Emory FXS Center

2023      Nisha Raj receives NIH R21 Exploratory/Developmental Research Grant Award (R21MH133823)

2023      Nisha Raj and Gary Bassell receives a Georgia CTSA i3 Synergy Cores pilot grant (Round #127 SOM I3 Synergy Cores)

2023      Nisha Raj receives an Emory URC Grant

2023      Gary Bassell is selected to be a member on the NIH NCATS Special Emphasis Panel on Understudied Proteins in Rare Diseases

2022      Adam Kosti receives the FRAXA Research Foundation Fellowship

2022      Nisha Raj receives NARSAD BBRF Young Investigator Grant 

2022      Ryan Purcell receives an Emory URC Grant

2022      Gary Bassell is selected to be a member on the NIH NIMH Silvio O. Conte Centers for Basic and Translational Research grant review panel

2021      Ryan Purcell receives NARSAD BBRF Young Investigator Grants 

2021      Kamyra Edokpolor receives the Myotonic Dystrophy Foundation (MDF) Research Fellowship

2020      Ryan Purcell receives NIH F32 Ruth L. Kirschstein Postdoctoral Individual National Research Service Award(F32MH124273)

2020      Luke Knudson receives NIH F31 Ruth L. Kirschstein Predoctoral Individual National Research Service Award (F31NS117086)

2020      Gary Bassell (Emory University) & Wang Lab (University of Florida)  receives MPI NIH R01 Research Project Grant (R01NS114253)

2020      Gary Bassell (Emory University) & Wang Lab (University of Florida)  receives MPI NIH R01 Research Project Grant (R01NS112291)