Faculty Publications


Phosphoinositide-dependent enrichment of actin monomers in dendritic spines regulatessynapse development and plasticity. Lei W, Myers KR, Rui Y, Hladyshau S, Tsygankov D, Zheng JQ. J Cell Biol. 2017 Jun 28. pii: jcb.201612042. doi: 10.1083/jcb.201612042. [Epub ahead of print]

The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors. Comstra HS, McArthy J, Rudin-Rush S, Hartwig C, Gokhale A, Zlatic SA, Blackburn JB, Werner E, Petris M, D'Souza P, Panuwet P, Barr DB, Lupashin V, Vrailas-Mortimer A, Faundez V. Elife. 2017 Mar 29;6. pii: e24722. doi: 10.7554/eLife.24722. PMID: 28355134.  

Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus. Larimore J, Zlatic SA, Arnold M, Singleton KS, Cross R, Rudolph H, Bruegge MV, Sweetman A, Garza C, Whisnant E, Faundez V. Front Genet. 2017 Mar 10;8:28. doi: 10.3389/fgene.2017.00028. eCollection 2017. PMID: 28344592.

The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly. Donlin-Asp PG, Fallini C, Campos J, Chou CC, Merritt ME, Phan HC, Bassell GJ, Rossoll W.  Cell Rep. 2017 Feb 14;18(7):1660-1673. doi: 10.1016/j.celrep.2017.01.059. PubMed PMID: 28199839.

Germ Cell-less Promotes Centrosome Segregation to Induce Germ Cell Formation. Lerit DA, Shebelut CW, Lawlor KJ, Rusan NM, Gavis ER, Schedl P, Deshpande G. Cell Rep. 2017 Jan 24;18(4):831-839. doi: 10.1016/j.celrep.2016.12.074. PubMed PMID: 28122234; PubMed Central PMCID: PMC5327791.


MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset. Gross C, Yao X, Engel T, Tiwari D, Xing L, Rowley S, Danielson SW, Thomas KT, Jimenez-Mateos EM, Schroeder LM, Pun RY, Danzer SC, Henshall DC, Bassell GJ. Cell Rep. 2016 Sep 27;17(1):37-45. doi: 10.1016/j.celrep.2016.08.074. PubMed PMID: 27681419; PubMed Central PMCID: PMC5061042.

Amyloid β oligomers elicit mitochondrial transport defects and fragmentation in a time-dependent and pathway-specific manner. Rui Y, Zheng JQ. Mol Brain. 2016 Aug 17;9(1):79. PMID: 27535553. 

Molecular organization of the desmosome as revealed by direct stochastic optical reconstruction microscopy. Stahley SN, Bartle EI, Atkinson CE, Kowalczyk AP, Mattheyses AL. J Cell Sci. 2016 Aug 1;129(15):2897-904. doi: 10.1242/jcs.185785. Epub 2016 Jun 17. PMID: 27505428.

Identification of consensus binding sites clarifies FMRP binding determinants. Anderson BR, Chopra P, Suhl JA, Warren ST, Bassell GJ. Nucleic Acids Res. 2016 Aug 19;44(14):6649-59. Epub 2016 Jul 4.  PMID: 27378784.

Upslope treadmill exercise enhances motor axon regeneration but not functional recovery following peripheral nerve injury. Cannoy J, Crowley S, Jarratt A, Werts KL, Osborne K, Park S, English AW. J Neurophysiol. 2016 Jul 27:jn.00129.2016. [Epub ahead of print] PMID: 27466130.

Selective Requirement for Maintenance of Synaptic Contacts onto Motoneurons by Target-Derived trkB Receptors. Zhu X, Ward PJ, English AW. Neural Plast. 2016;2016:2371893. Epub 2016 Jun 28. PMID: 27433358.

Optically-Induced Neuronal Activity Is Sufficient to Promote Functional Motor Axon Regeneration In Vivo. Ward PJ, Jones LN, Mulligan A, Goolsby W, Wilhelm JC, English AW. PLoS One. 2016 May 6;11(5):PMID: 27152611.

Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons. Fallini C, Donlin-Asp PG, Rouanet JP, Bassell GJ, Rossoll W. J Neurosci. 2016 Mar 30;36(13):3811-20. PMID: 27030765.

hnRNP-Q1 represses nascent axon growth in cortical neurons by inhibiting Gap-43 mRNA translation. Williams KR, McAninch DS, Stefanovic S, Xing L, Allen M, Li W, Feng Y, Mihailescu MR, Bassell GJ. Mol Biol Cell. 2016 Feb 1;27(3):518-34. Epub 2015 Dec 10. PMID: 26658614.

Super-Resolution Microscopy Reveals Altered Desmosomal Protein Organization in Tissue from Patients with Pemphigus Vulgaris. Stahley SN, Warren MF, Feldman RJ, Swerlick RA, Mattheyses AL, Kowalczyk AP. J Invest Dermatol. 2016 Jan;136(1):59-66. doi: 10.1038/JID.2015.353. PMID: 26763424.

Maternally provided LSD1/KDM1A enables the maternal-to-zygotic transition and prevents defects that manifest postnatally. Wasson JA, Simon AK, Myrick DA, Wolf G, Driscoll S, Pfaff SL, Macfarlan TS, Katz DJ. Elife. 2016 Jan 27;5. PMID: 26814574 .


A 3' untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA-binding protein HuR. Suhl JA, Muddashetty RS, Anderson BR, Ifrim MF, Visootsak J, Bassell GJ, Warren ST., Proc Natl Acad Sci U S A. 2015 Nov 9. pii: 201514260. [Epub ahead of print]

Dysregulation and restoration of translational homeostasis in fragile X syndrome. Richter JD, Bassell GJ, Klann E. Nat Rev Neurosci. 2015 Oct;16(10):595-605. Epub 2015 Sep 9.

Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor. Gokhale A, Vrailas-Mortimer A, Larimore J, Comstra HS, Zlatic SA, Werner E, Manvich DF, Iuvone PM, Weinshenker D, Faundez V. Hum Mol Genet. 2015 Oct 1;24(19):5512-23. Epub 2015 Jul 21. PMID: 26199316.

Fragile X mental retardation protein interactions with a G quadruplex structure in the 3'-untranslated region of NR2B mRNA. Stefanovic S, DeMarco BA, Underwood A, Williams KR, Bassell GJ, Mihailescu MR. Mol Biosyst. 2015 Sep 28. [Epub ahead of print] PMID:26412477.

Real-time fluorescence imaging with 20 nm axial resolution. Stabley DR, Oh T, Simon SM, Mattheyses AL, Salaita K. Nat Commun. 2015 Sep 22;6:8307. PMID: 26392382. 

PABPN1 suppresses TDP-43 toxicity in ALS disease models. Chou CC, Alexeeva OM, Yamada S, Pribadi A, Zhang Y, Mo B, Williams KR, Zarnescu DC, Rossoll W. Hum Mol Genet. 2015 Sep 15;24(18):5154-73. Epub 2015 Jun 30. PMID: 26130692.

The ecdysone receptor coactivator Taiman links Yorkie to transcriptional control of germline stem cell factors in somatic tissue. Zhang C, Robinson BS, Xu W, Yang L, Yao B, Zhao H, Byun PK, Jin P, Veraksa A, Moberg KH. Dev Cell. 2015 Jul 27;34(2):168-80. doi: 10.1016/j.devcel.2015.05.010. Epub 2015 Jul 2. PMID: 26143992. 

Identification of a lipid scrambling domain in ANO6/TMEM16F. Yu K, Whitlock JM, Lee K, Ortlund EA, Cui YY, Hartzell HC. Elife 2015 Jun 9. PMID: 26057829 PMCID: PMC4477620.
The N-ethylmaleimide-sensitive factor and dysbindin interact to modulate synaptic plasticity. Gokhale A, Mullin AP, Zlatic SA, Easley CA 4th, Merritt ME, Raj N, Larimore J, Gordon DE, Peden AA, Sanyal S, Faundez V. J Neurosci. 2015 May 13;35(19):7643-53. PMID: 25972187.