Pallavi Bhattaram, PhD

Adjunct Assistant Professor

Department of Cell Biology

Adjunct Assistant Professor

Department of Orthopaedics

Professor

Department of Cell Biology

Office: Veteran's Affairs Medical Center

Email: pallavi.bhattaram@emory.edu

Office Location:

Research Focus

Our research program is directed towards understanding the complex molecular networks governing the pathophysiology of musculoskeletal diseases, especially osteoarthritis and rheumatoid arthritis. Our goal is to identify novel molecular therapeutic targets for improving the treatment of disabling skeletal diseases. We are applying the knowledge gained from studies on embryonic skeleton development towards uncovering the aberrant molecular mechanisms that lead to skeletal disease. While, studies of the roles of SOX transcription factors in skeletal development and disease are a major part of our current research program, we are also focusing on other biological factors that play key roles in skeletogenesis and pathogenesis of musculoskeletal diseases.

Honors:

2010

Postdoctoral Research Fellow. Laboratory of Dr. Véronique Lefebvre, Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.

Research Associate. Laboratory of Dr. Véronique Lefebvre, Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.

Project Staff, Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.

Assistant Professor of Molecular Medicine, Cleveland Clinic Lerner College of Medicine (CCLCM) of Case Western Reserve University, Cleveland, OH

Assistant Professor, Department of Orthopaedics, Emory University School of Medicine, Atlanta, GA

Dr. William E. Lower award for outstanding paper in scientific investigation, Cleveland Clinic, Cleveland, USA.

  1. 2011  

Elsa Albrecht Research Achievement award from the Department of Cell Biology, Cleveland Clinic, Cleveland, USA.

  1. 2012  
    Best poster award at annual Lerner Research Retreat

  2. 2013  
    Abstract selected for oral presentation at Gordon Research Conference: Cartilage Biology and Pathology, Le Diableretes, Switzerland.

  3. 2014  
    Abstract selected for oral presentation for oral presentation at Gordon Research Seminar: Bones and Teeth, Galveston, Texas, USA

  1. 2014  
    Gloria Lockhart Memorial Fellow from Arthritis National Research Foundation

  2. 2015  
    Elsa Albrecht Research Achievement Award from the Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, OH.

  3. 2015
    Chair 2015 Gordon Research Seminar: Cartilage Biology and Pathology, Galveston, Texas, USA

  1. 2015  
    Best poster award, Gordon Research Conference on Cartilage Biology and Pathology, Galveston, TX.

  2. 2016  
    John Vaughan Scholar from Arthritis National Research Foundation

Research Support Ongoing Research Support:

NIH/NIAMS R01 AR070736 (Role: PI)
Award period: 09/06/2017-08/31/2022
Title: Elucidation of mechanisms governing the activities of synovial fibroblasts
Brief statement of project goal: This project will investigate the contributions of SOXC proteins in the aggressive transformation of fibroblast-like synoviocytes that occurs in response to inflammatory cytokines in such chronic joint degenerative diseases as rheumatoid arthritis.

Recently Completed Research Support:

Rheumatology Research Foundation Grant
Award period: 07/01/2016-06/31/2018 (Role: co-PI)
Title: Quality-by-design approach to generate synovial cells from pluripotency
Brief statement of project goal: To develop FDA-compliant and fully automated procedures to generate synovial fibroblasts and from patient-derived induced pluripotent stem cells.

Arthritis National Research Foundation Grant
Award period: 07/01/2014-06/31/2016 (Role: PI)
Title: Roles of SOXC genes in synovial fibroblasts during rheumatoid arthritis.
Brief statement of project goal: To establish the involvement of SOXC genes in rheumatoid arthritis pathology.

 

 

Publications