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For the most recent list of publications, please click here.

Jones, C., Roper, V.C., Foucher, I., Qian, D., Banizs, B., Petit, C., Yoder, B., Chen, P. (2008) Ciliary genes link basal body polarization to planar cell polarity regulation. Nature Genetics 40, 69-77.


Ahmad S, Tang W, Chang Q, Qu Y, Hibshman J, Li Y, Söhl G, Willecke K, Chen P, Lin X., (2007) Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness. Proc Natl Acad Sci U S A. 104(4), 1337-41.


Qu Y, Tang W, Dahlke I, Ding D, Salvi R, Söhl G, Willecke K, Chen P, Lin X., (2007) Analysis of connexin subunits required for the survival of vestibular hair cells. J Comp Neurol. 504(5), 499-507.


Jones C, Chen P., (2007) Planar cell polarity signaling in vertebrates. Bioessays. 29(2), 120-32.


Qian D, Jones C, Rzadzinska A, Mark S, Zhang X, Steel KP, Dai X, Chen P., (2007) Wnt5a functions in planar cell polarity regulation in mice. Dev Biol. 306(1), 121-33.


Kelly M, Chen P., (2007) Shaping the mammalian auditory sensory organ by the planar cell polarity pathway. Int J Dev Biol. 51(6-7), 535-47.


Wang J, Hamblet NS, Mark S, Dickinson ME, Brinkman BC, Segil N, Fraser SE, Chen P, Wallingford JB, Wynshaw-Boris A., (2006) Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development. 133, 1767-1778.


Qian D., Radde-Gallwitz K., Kelly M., Tyrberg B., Kim J., Gao W., Chen P., (2006) Basic Helix–Loop–Helix Gene Hes6 Delineates the Sensory Hair Cell Lineage in the Inner Ear. Dev. Dynamics. March


Tang W., Zhang Y., Chang Q., Ahmad S., Dahlke I., Yi H., Chen P., Paul D.L., Lin X., (2006) Connexin29 Is Highly Expressed in Cochlear Schwann Cells, and It Is Required for the Normal Development and Function of the Auditory Nerve of Mice. J. Neuroscience 26(7), 1991-1999.


Zhang Y., Tang W., Ahmad S., Sipp J.A., Chen P., Lin X., (2005) Gap-Junction mediated intercellular biochemical coupling in cochlear supporting cells is required for normal cochlear functions. Proc Natl Acad Sci USA. 102(42), 15201-15206.


Wang J., Mark S., Zhang X., Qian D., Yoo S.J., Radde-Gallwitz K., Zhang Y., Lin X., Collazo A., Wynshaw-Boris A., Chen P. (2005) Regulation of Polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nat Genet. 37(9) 980-5


Sun, J., Ahmad, S., Chen, S., Tang, W., Zhang, Y., Chen, P., and Lin, X. (2005) Cochlear gap junctions co-assembled from connexins 26 and 30 show faster intercellular Ca++ signaling than their homomeric counterparts. Amer J Physiol. Cell Physiol. 288, C613-23.


Peng, B., Ahmad, S., Chen, S., Chen, P., Price, M., and Lin, X. (2004) Acid-Sensing Ion Channel 2 Contributes a Major Component to Acid-Evoked Excitatory Responses in Spiral Ganglion Neurons and Plays a Role in Noise Susceptibility of Mice. J. Neuroscience 24,10167-10175.


Radde-Gallwitz, K., Pan, L., Gan, L., Lin, X., Segil, N., and Chen, P. (2004) Expression of Islet1 Marks the Sensory and Neuronal Lineages in the Mammalian Inner ear. J. Comp. Neuro. 477,412-421.


Peng, B.G., Li, Q., Chen, S., Ahmad, S., Chen, P., Lin, X. (2004) Metabotropic glutamate receptors contribute to excitatory neurotransmissions in the cochlea. Neuroscience 123, 221-30.


P. Chen, F. Zindy, C. Abdala, F. Liu, X. Li, M. F. Roussel, and N. Segil. (2003) Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d. Nature Cell Biology 5, 422-426. Comments/News and Views: 385-387.


E.A. Lumpkin, T. Collisson, P. Parab, A. Omar-Abdalla, H. Haeberle, P. Chen, A. Doetzlhofer, P. White, A. Groves, N. Segil, and J. E. Johnson. (2003) Math1-driven GFP Expression in the Developing Nervous System of Transgenic Mice. Gene Expr. Patterns 3, 389-95.


P. Chen, J. E. Johnson, H. Y. Zoghbi, and N. Segil (2002) The role of Math1 in inner ear development, uncoupling the establishment of the sensory primordium from hair cell fate determination. Development 129, 2495-2505.


D. Huang, P. Chen, S. Chen, M. Nagura, D. Lim, and X. Lin (2002) Expression patterns of aquaporins in the inner ear: evidence for concerted actions of multiple types of aquaporins to facilitate water transport in the cochlea. Hearing Res. 165, 85-95.


X. Lin, S. Chen, and P. Chen (2000) Metabotropic GABAB receptors are expressed in spiral ganglion neurons of mice. NeuroReport 11, 957-961.


P. Chen and N. Segil (1999) p27Kip1 links cell proliferation to morphogenesis in the developing organ of Corti. Development 126, 1581-1590.


P. Chen and M. Hochstrasser (1996) Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly. Cell 86, 961-972.


P. Chen and M. Hochstrasser (1995) Biogenesis, structure and function of the yeast 20S proteasome. EMBO J. 14, 2620-30.


M. Hochstrasser, F. Papa, P. Chen, S. Swaminathan, P. Johnson, L. Stillman, A. Y. Amerik, and S.-J. Li (1995) The DOA pathway: studies on the functions and mechanisms of ubiquitin-dependent protein degradation in the yeast Saccharomyces cerevisiae. Cold Spring Harbor Symposia on Quantitative Biology Volume LX.


P. Chen, P. Johnson, T. Sommer, S. Jentsch, and M. Hochstrasser (1993) Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATa2 repressor. Cell 74, 357-369.


K. S. Quandt, F. Xu, P. Chen, and D. E. Hultquist (1991) Evidence that the protein components of bovine erythrocyte green heme binding protein and flavin reductase are identical. Biochem. Biophy. Res. Commu. 178, 315-21.


Y. Wang, P. Chen, X. Wu, A. Sun, H. Wang, Y. Zhou, and Z. Li (1990) A new enhancer element, ENII, identified in the X-gene of Hepatitis B virus. J. of Virology 64, 3977-81.