Lab News

Collaboration with McEachin lab publication in Acta Neuropathologica
The Bassell and McEachin lab published, “Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains,” in Acta Neuropathologica.

Aleksandra Janusz-Kaminska of the Bassell Lab publishes paper in Molecular Biology of the Cell
Aleksandra Janusz-Kaminska and colleagues publish, “Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner,” in Molecular Biology of the Cell.

@BassellLab and @EricTWang Publish Collaborative Nature Communications Paper Supported by MPI NIH R01 grant
The Bassell Lab and Wang Lab published, "Muscleblind-like proteins use modular domains to localize RNAs by riding kinesins and docking to membranes," by Ryan P. Hildebrandt and Kathryn R. Moss et al.

 

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Bassell Lab group 2023

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In MEMORY OF KUN LIN

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With a heavy heart we communicate the recent tragic passing of my graduate student, our colleague and friend, Kun Lin, on February 12, 2021. Our tears and sadness are hard. Kun was full of radiant energy, intellect and passion, kind and generous, with dreams to become a professor. To learn more about Kun's short but wonderful life, to share your thoughts and contributions:

GOFUNDME - To provide support to Kun's parents for medical, funeral, and other costs, please visit.

KUDOBOARD - to share your thoughts and photos about Kun.

KUN LIN MEMORIAL SCHOLARSHIP FUND

MEMORIAL BENCH - To contribute to the Kun Lin Memorial Bench, please donate to the Atlanta Botanical Garden (Kun’s favorite place in Atlanta, GA). Please indicate donations are “In memory of Kun Lin”.

THE KUN LIN MEMORIAL LECTURE:

We are grateful for the kind and generous donations from faculty, students and friends to establish the Kun Lin Memorial lecture. The lecture topics will relate to Kun's research interests in cellular and brain imaging, and RNA and synapse biology in health and disease.

-Gary J. Bassell, PhD, Professor and Chair

Highlights

Gary Bassell and Eric Wang Receive NINDS Funding for Collaborative Research on Myotonic Dystrophy

Drs. Bassell and Wang The National Institute of Neurological Disorders and Stroke has awarded Bassell’s and Wang’s laboratories $2.2 million over five years to examine the neuronal function of Muscleblind-like proteins, which play key roles in myotonic dystrophy.

Read full story in Emory Health Sciences Blog.

LISTEN to a joint talk recently presented by Gary Bassell and Eric Wang at the RNA Society annual meeting in May 2020.

Recent Publications

Kosti A, Bassell GJ. Where to start? Activity-dependent alternative translation initiation generates multifunctional proteoforms in the brain. Mol Cell. 2024 Oct 17;84(20):3863-3865. doi: 10.1016/j.molcel.2024.09.029. PMID: 39423793.

Zakutansky PM, Ku L, Zhang G, Shi L, Li Y, Yao B, Bassell GJ, Read RD, Feng Y. Isoform balance of the long noncoding RNA NEAT1 is regulated by the RNA-binding protein QKI, governs the glioma transcriptome, and impacts cell migration. J Biol Chem. 2024 Aug;300(8):107595. doi: 10.1016/j.jbc.2024.107595. Epub 2024 Jul 18. PMID: 39032650; PMCID: PMC11367543.

Janusz-Kaminska A, Brzozowska A, Tempes A, Urbanska M, Blazejczyk M, Miłek J, Kuzniewska B, Zeng J, Wesławski J, Kisielewska K, Bassell GJ, Jaworski J. Rab11 regulates autophagy at dendritic spines in an mTOR- and NMDA-dependent manner. Mol Biol Cell. 2024 Mar 1;35(3):ar43. doi: 10.1091/mbc.E23-02-0060. Epub 2024 Jan 31. PMID: 38294869; PMCID: PMC10916872.

Chung M, Carter EK, Veire AM, Dammer EB, Chang J, Duong DM, Raj N, Bassell GJ, Glass JD, Gendron TF, Nelson PT, Levey AI, Seyfried NT, McEachin ZT. Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains. Acta Neuropathol. 2024 Feb 3;147(1):29. doi: 10.1007/s00401-023-02671-0. PMID: 38308693; PMCID: PMC10838224.

Purcell RH, Sefik E, Werner E, King AT, Mosley TJ, Merritt-Garza ME, Chopra P, McEachin ZT, Karne S, Raj N, Vaglio BJ, Sullivan D, Firestein BL, Tilahun K, Robinette MI, Warren ST, Wen Z, Faundez V, Sloan SA, Bassell GJ, Mulle JG.Cross-species transcriptomic analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion. Sci Adv. 2023 Aug 18;9(33):eadh0558. doi: 10.1126/sciadv.adh0558. Epub 2023 Aug 16. PMID: 37585521; PMCID: PMC10431714.

Hildebrandt RP, Moss KR, Janusz-Kaminska A, Knudson LA, Denes LT, Saxena T, Boggupalli DP, Li Z, Lin K, Bassell GJ, Wang ET. Muscleblind-like proteins use modular domains to localize RNAs by riding kinesins and docking to membranes. Nat Commun. 2023;14(1):3427. Published 2023 Jun 9. doi:10.1038/s41467-023-38923-6.

View More Publications >>

Honors, awards, and fellowships  

2024

Tony Chung receives the 2024 Cell Biology Spotlight Trainee

Maxine Robinette receives the 2024 Cell Biology Spotlight Trainee

Ryan Purcell establishes the Purcell Lab at Virginia Tech Carilion Research Institute

Betty Bekele receives the Win Sale Travel Award & the Kun Lin Travel award to attend conferences

Maxine Robinette receives the Win Sale Travel Award & the Kun Lin Travel award to attend conferences

Luke Knudson defends his dissertation and is awarded his Doctor of Philosophy degree (Bassell defense #16)

Maxine Robinette receives NIH R36 Dissertation Award (R36MH136806)
Gary Bassell receives NIH R03 Small Research Grant (R03MH135518)

2023

Betty Bekele receives the Myotonic Dystrophy Foundation (MDF) Research Fellowship 

Nisha Raj is promoted to Assistant Professor of Human Genetics with secondary appointment in Cell Biology

Ryan Purcell is promoted to Assistant Professor of Cell Biology

2022

Kamyra Edokpolor defends her dissertation and is awarded her Doctor of Philosophy degree (Bassell defense #15)

Nisha Raj is selected as a 2022 Cell Biology Spotlight Traineee
2021
Kamyra Edokpolor is selected as a 2021 Cell Biology Spotlight Trainee

Zachary McEachin is promoted to Assistant Professor of Human Genetics with secondary appointment in Cell Biology

Pernille Bulow defends her dissertation and is awarded her Doctor of Philosophy degree (Bassell defense #14)

2020

Penny Bulow is selected as a 2020 Cell Biology Spotlight Trainee 

Austin Lai is selected as a 2020 Cell Biology Spotlight Trainee 

2019

Phillip Price defends his dissertation and is awarded his Doctor of Philosophy degree (Bassell defense #13)

Arielle Valdez-Sinon defends her dissertation and is awarded her Doctor of Philosophy degree (Bassell defense #12)

Chao Lin defends his dissertation and is awarded his Doctor of Philosophy degree (Bassell defense #11)

Zachary McEachin defends his dissertation and is awarded his Doctor of Philosophy degree (Bassell defense #10)

Nisha Raj defends her dissertation and is awarded her Doctor of Philosophy degree (Bassell defense #9)